RAP 85

There is a short-term (15 min) protective effect against hypotension when pre-treating with high dose IV calcium prior to giving diltiazem to patients with a-fib.

The benefit of 1:1:1 transfusion ratio is concentrated among patients with thoracic bleeding rather than abdominopelvic bleeding. Current practice of 1:1:1 transfusion for patients with massive transfusion should remain, but physicians might use this information to be particularly sure that this ratio is maintained in thoracic bleeding.

Correcting severe hyponatremia at a faster rate (8-10 mEq) in the first 24 hours was associated with a significantly lower in-hospital mortality but higher rates of ODS (though not significant) compared to standard correction rate (6-8 mEq). However, this finding is undermined by poor quality data and high risk of bias. Furthermore, this does not apply to emergency management of severe symptomatic hyponatremia. 

Maternal outcomes overall are poor with one survivor after 29 min of CPR, but neonatal survival is more likely and can happen after longer durations of CPR (47 min).