RAP 63
1) The PLUS Study (Balanced multielectrolyte solution vs Saline in critically ill adults)
Review Summary
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Source:
- Authors: Finfer, MD, et al.
- Reviewer: Nick Maelska, MD
Takeaway
Critically ill emergency department patients without significant brain injury can be safely fluid resuscitated with either balanced crystalloids or normal saline without a large difference in patient-centered outcomes.
2) Time-to-Disposition Intervals
Review Summary
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Source:
- Authors: B Stenson, P Antkowiak, L Balaji, et al.
- Reviewer: Heather Kaluzniak, MD
Takeaway
In a single center, residents dispositioned patients ~38 min. faster later in shifts. There was no clinical data. Further study could clarify motivations & effects. By itself, this is a good phenomenon to be aware of.
3) Time to Treatment with Anti-Arrhythmics and ROSC
Review Summary
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Source:
- Author: Mike Menchine, MD
- Reviewer: Abdihakim Abdullahi, MD
Takeaway
Early administration of amiodarone may lead to higher chances of ROSC in patients with refractory out of hospital VF/VT but late administration may be detrimental. Data insufficient to make that conclusion but further research is warranted. Ultimately the chances of ROSC decreased over time for all 3 agents including placebo.
4) The CLASSIC Trial: IV fluid restriction in septic shock
Review Summary
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Source:
- Author: Salim Rezaie, MD
- Reviewer: Brett Milbrandt, MD
Takeaway
Initial IVF resuscitation in sepsis is key; ensure patients receive 30cc/kg by ideal body weight. Further IVF is less critical, just don’t drown them.
5) Post-Roe v. Wade
Review Summary
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Source:
- Authors: Rita Rubin, Jennifer Abbasi
- Reviewer: Jacy O'Keefe, MD
Takeaway
Emergency physicians should be prepared to provide critical lifesaving treatment after unsafe abortions.