RAP 63

1) The PLUS Study (Balanced multielectrolyte solution vs Saline in critically ill adults)

Review Summary

  • Source: New England Journal
  • Authors: Finfer, MD, et al.
  • Reviewer: Nick Maelska, MD
3
/ 7
BEEM Rater Scale
4
/ 7
Educational Utility
6
/ 7
Evidence Based Medicine

Takeaway

Critically ill emergency department patients without significant brain injury can be safely fluid resuscitated with either balanced crystalloids or normal saline without a large difference in patient-centered outcomes.

2) Time-to-Disposition Intervals

Review Summary

  • Source: American Journal of EM
  • Authors: B Stenson, P Antkowiak, L Balaji, et al.
  • Reviewer: Heather Kaluzniak, MD
4
/ 7
BEEM Rater Scale
4
/ 7
Educational Utility
3
/ 7
Evidence Based Medicine

Takeaway

In a single center, residents dispositioned patients ~38 min. faster later in shifts. There was no clinical data. Further study could clarify motivations & effects. By itself, this is a good phenomenon to be aware of. 

3) Time to Treatment with Anti-Arrhythmics and ROSC

Review Summary

  • Source: EMA
  • Author: Mike Menchine, MD
  • Reviewer: Abdihakim Abdullahi, MD
2
/ 7
BEEM Rater Scale
3
/ 7
Educational Utility
3
/ 7
Evidence Based Medicine

Takeaway

Early administration of amiodarone may lead to higher chances of ROSC in patients with refractory out of hospital VF/VT but late administration may be detrimental. Data insufficient to make that conclusion but further research is warranted. Ultimately the chances of ROSC decreased over time for all 3 agents including placebo. 

4) The CLASSIC Trial: IV fluid restriction in septic shock

Review Summary

  • Source: REBEL EM
  • Author: Salim Rezaie, MD
  • Reviewer: Brett Milbrandt, MD
3
/ 7
BEEM Rater Scale
3
/ 7
Educational Utility
5
/ 7
Evidence Based Medicine

Takeaway

Initial IVF resuscitation in sepsis is key; ensure patients receive 30cc/kg by ideal body weight. Further IVF is less critical, just don’t drown them.

5) Post-Roe v. Wade

Review Summary

  • Source: JAMA
  • Authors: Rita Rubin, Jennifer Abbasi
  • Reviewer: Jacy O'Keefe, MD
7
/ 7
BEEM Rater Scale
5
/ 7
Educational Utility
4
/ 7
BEEM Rater Scale

Takeaway

Emergency physicians should be prepared to provide critical lifesaving treatment after unsafe abortions.