RAP 78
1) Cefepime vs pip-tazobactam in adults hospitalized for acute infection: the ACORN trial
Review Summary
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Source:
- Author: Samuel Rouleau
- Reviewer: Sarah Hackworthy, PA-C
3
BEEM Rater Scale
3
Educational Utility
4
Evidence Based Medicine
Takeaway
Selecting cefepime as an alternative to Zosyn (when combined with vancomycin) does not appear to impact renal function.
2) High- versus low-dose IV nitroglycerin for SCAPE
Review Summary
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Source:
- Author: Justin Morgenstern, MD
- Reviewer: Alayna Kabanuk, MD
5
BEEM Rater Scale
5
Educational Utility
4
Evidence Based Medicine
Takeaway
High-dose nitroglycerin has better outcomes compared to low-dose nitroglycerin and should be used in conjunction with BiPAP in patients presenting with SCAPE.
3) Antibiotic Prophylaxis For Chest Tube Placement in Trauma
Review Summary
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Source:
- Author: Sanjay Arora, MD
- Reviewer: David Perez-Molinar, MD
4
BEEM Rater Scale
3
Educational Utility
5
Evidence Based Medicine
Takeaway
Antibiotic prophylaxis following tube thoracostomy placement for traumatic pneumothorax/hemothorax may be beneficial in reducing the incidence of empyema.
4) Serious bacterial infection in pre-term infants: should their age be “corrected”?
Review Summary
-
Source:
- Author: Sanjay Arora, MD
- Reviewer: Jesse Brooks, MD
3
BEEM Rater Scale
3
Educational Utility
3
Evidence Based Medicine
Takeaway
Corrected age may be a better indicator of SBI risk than chronologic age. Most relevant for those with chronologic age > 3 months, but corrected age < 3 months.
5) The PALACE trial: direct oral PCN challenge in patients with low-risk PCN allergy
Review Summary
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Source:
- Author: Salim Rezaie, MD
- Reviewer: Kurt Isenberger, MD
6
BEEM Rater Scale
5
Educational Utility
7
Evidence Based Medicine
Takeaway
In patients with low-risk history, direct oral PCN challenge is a safe procedure to facilitate the removal of a PCN allergy label.